Burdyga, T.     Seeing is believing! Live confocal imaging of microvascular networks in situ: morphology, Ca2+ signalling and tone [Text] / T. Burdyga, L. Borysova // Укр. біохім. журн. - 2013. - Т. 85, N 6. - P129-133 Рубрики: МИКРОСОСУДЫ--MICROVESSELS    МИКРОСКОПИЯ КОНФОКАЛЬНАЯ--MICROSCOPY, CONFOCAL Аннотация: 2- and 3-dimensional confocal imaging of Fluo-4 loaded ureteric microvesells in situ allowed us to demonstrate distinct morphology, Ca2+ signalling and contractility in myocytes of arcade arterioles and pericytes of arcade venules. In myocytes and pericytes, Ca2+ signals arise exclusively from Ca2+ release from the sarcoplasmic reticulum through inositol 1,4,5-trisphosphate receptors. Са2+ transients in pericytes are less oscillatory, slower and longer-lasting than those in myocytes. The data obtained suggest differences in the mechanisms controlling local blood flow in precapillary arterioles and postcapillary venules. Доп.точки доступа: Borysova, L. Экз-ры: