Macro- and microelements determination in children with rotavirus infection [] / O. I. Smiyan [et al.] // Запорож. мед. журн. - 2018. - Том 20, N 3. - С. 371-374 MeSH-главная: РОТАВИРУСНЫЕ ИНФЕКЦИИ -- ROTAVIRUS INFECTIONS (диагностика, лекарственная терапия, этиология) МИКРОЭЛЕМЕНТЫ -- TRACE ELEMENTS (анализ, кровь) ДЕТЕЙ ОХРАНЫ ЗДОРОВЬЯ СЛУЖБЫ -- CHILD HEALTH SERVICES Аннотация: The purpose of this study was to determine serum zinc, iron, magnesium, copper, potassium, calcium, and sodium levels in acute rotavirus infection and convalescence period in children. Materials and methods. We examined 86 patients aged from 4 months to 5 years with clinical and laboratory signs of rotavirus infection. The I group – 43 children with RVI in acute period. The II group – 43 children with RVI in convalescence period. Thecontrol group included 14 healthy children at the same age. The content of macro- and microelements (zinc, iron, magnesium,copper, potassium, calcium and sodium) in blood serum was determined by atomic absorption spectrophotometry. Feces sampleswere used for Cito Test Rota (Pharmasco). Cito test was used for rotavirus antigen detection in feces. Statistical analysis wasperformed by Excel. Student’s t-test was used to evaluate differences between study groups. Results. The acute period of the disease in children with rotavirus infection was characterized by a significant increase of copper in blood serum compared with the control group. At the same time, a significant decrease of iron, magnesium, zinc, potassium,calcium, sodium were determined in patients with rotavirus infection, compared with apparently healthy children. After standardtreatment only the indicators of magnesium, potassium and sodium reached the same indices of control group children. Conclusions. The detected changes in the mineral status of patients with rotavirus infection suggest the need for treatment correction. Correction of micro- and macroelements imbalances in patients with rotavirus infection possibly should be aimed atthe metallo-drugs inclusion in complex treatment as well as medicines which improve absorption of the latter in the intestine. Доп.точки доступа: Smiyan, O. I.; Smiyan-Horbunova, K. O.; Loboda, A. M.; Popov, S. V.; Bynda, T. P.; Vysotsky, I. Yu.; Sichnenko, P. I.; Petrashenko, V. O.; Man'ko, Yu. A.; Kosarchuk, V. V.; Gordienko, O. V. Экз-ры: